Generation of oncogenic type C viruses: Rapidly leukemogenic viruses derived from C3H mouse cells in vivo and in vitro

Generation of oncogenic type C viruses: rapidly leukemogenic viruses derived from C3H mouse cells in vivo and in vitro.

A type C virus was isolated from C3H/10T1/2 mouse cells in culture after activation with iododeoxyuridine. This virus was poorly infectious for mouse cells and did not cause tumors upon inoculation into newborn NIH Swiss mice. Variants with increased infectivity for mouse cells were then derived both in vivo and in vitro by selecting for variants able to grow to high titers. The highly infectio...

Viral genes involved in leukemogenesis. I. Generation of recombinants between oncogenic and nononcogenic mouse type-C viruses in tissue culture

An approach toward elucidation of the mechanisms of action of mammalian leukemia viruses has been made by the generation in tissue culture of recombinant viruses between a potent murine leukemia virus (MuLV), Rauscher-MuLV, and an endogenous xenotropic mouse type-C virus, BALB:virus-2, without known malignant potential. Using a double selection system devised to select against the temperature-s...

Oncogenic Viruses

Lepista sordida Water Extract Enhances the Maturation of Mouse Dendritic Cells in Vitro and in Vivo

synthesis of sulfides from alcohols and thiols in solvent-freeconditions and deoxygenation of sulfoxides

کاتالیست یک سنتز جدید برای تیواترها توصیف شده است. واکنش الکل ها با آریل، هتروآریل و آلکیل تیو ل ها درحضور 1،3،5- تری آزو- 2،4،6- تری فسفرین-2،2،4،4،6،6 هگزاکلراید ((tapc به عنوان یک کاتالیست موُثر، بازده های خوب تا عالی از تیواترها را حاصل می کند. علاوه براین، واکنش تحت شرایط بدون فلز و بدون حلال پیش می رود، بنابراین یک مکمل جالب برای روش های شناخته شده سنتز تیواترها ارائه می دهد. یک مکانیسم ا...